Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Diabetes and Vascular Disease Research
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Safley, D. M
Right arrow Articles by Marso, S. P
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Safley, D. M
Right arrow Articles by Marso, S. P
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Success rates of percutaneous coronary intervention of chronic total occlusions and long-term survival in patients with diabetes mellitus

David M Safley

Division of Cardiology and Biostatistics Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, US

John A House

Division of Cardiology and Biostatistics Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, US

Barry D Rutherford

Division of Cardiology and Biostatistics Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, US

Steven P Marso

Division of Cardiology and Biostatistics Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, US

The objectives of this study were to evaluate angiographic and clinical outcomes among patients with diabetes mellitus (DM) who underwent percutaneous coronary intervention (PCI) for a chronic total occlusion (CTO). We compared them with matched patients undergoing PCI of a non-CTO lesion. All patients had documented DM. Matching was performed using a propensity score for CTO.

There were 506 patients with DM and CTO who were matched with a non-CTO group. Results showed that angiographic success rates were lower with CTO (75% vs. 93%, p<0.001). In-hospital major adverse cardiac event (MACE Â death, urgent bypass surgery, Q-wave myocardial infarction or target vessel revascularisation) rates were equivalent (CTO 3.2% vs. non-CTO 2.6%, p=0.57). Survival was not different five years after revascularisation of CTO (75%) vs. non-CTO (79%) (p=0.20). In addition, when DM patients with CTO were analysed according to angiographic success of PCI, there were no significant differences in either in-hospital (success 1.6% vs. failure 2.4%, p=0.7) or 1-year mortality (success 22.2% vs. failure 26.8%, p=0.3).

We conclude that PCI of CTO is safe in patients with DM. Angiographic failure is not associated with an increase in MACE rates or mortality as compared to matched nonCTO patients. However, there is not a measurable improvement in survival in this DM-CTO population.

Key Words: percutaneous coronary intervention • chronic

Diabetes and Vascular Disease Research, Vol. 3, No. 1, 45-51 (2006)
DOI: 10.3132/dvdr.2006.006
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 J Am Coll Cardiol IntvHome page
D. M. Safley, J. A. House, S. P. Marso, J. A. Grantham, and B. D. Rutherford
Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel
J. Am. Coll. Cardiol. Intv., June 1, 2008; 1(3): 295 - 302.
[Abstract] [Full Text] [PDF]